Engineered leucine zippers show that hemiphosphorylated CREB complexes are transcriptionally active.
نویسندگان
چکیده
منابع مشابه
Engineered leucine zippers show that hemiphosphorylated CREB complexes are transcriptionally active.
The ability of basic/leucine zipper transcription factors to form homo- and heterodimers potentially increases the diversity of signaling pathways that can impinge upon a single genetic element. The capacity of these proteins to dimerize in various combinations complicates the analysis of their functional properties, however. To simplify the functional analysis of CREB dimers, we mutated select...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1993
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.90.19.9046